Phillip J. AlbrechtDr. Albrecht has 20 years of experience in biotechnology/pharmaceutical industry and academic research settings. During the early 1990's as a member of the neurotoxicology department at Genentech, Inc., Dr. Albrecht performed behavioral and sensory neurotoxicology and safety research studies, monitored contract lab toxicology study reports, and wrote documents in support of FDA submissions.

While conducting dissertation research at Penn State Hershey, Dr. Albrecht was focused on the molecular mechanisms of glial scar formation following disease and trauma. The work included genomic (RNA) and protein characterizations using standard molecular techniques, including extensive immunofluorescent microscope evaluations.

Dr. Albrecht received post-doctoral training at Georgetown University, where he developed a novel in vitro assay of primary fibroblast and astrocyte interaction. Using this model, investigations of the molecular mechanisms of scar formation were conducted, including multi-label immunochemical assessments of the Eph/ephrin signaling system.

In 2003, Dr. Albrecht relocated to Albany where he received additional training at the Center for Neuropharmacology & Neuroscience, focused on descending pain modulatory pathways and peripheral sensory systems. In 2005, Dr. Albrecht became an active research and teaching faculty member of the CNN. Working directly with Intidyn co-founder Dr. Frank Rice, his research has been instrumental to the understanding of peripheral mechanisms of chronic pain, and have been essential to the generation of novel views on theories of pain perception emerging from this research hub.

Implementing a translational research platform, Dr. Albrecht has been involved with projects utilizing cultured cells, rodents, monkeys, and humans to investigate cutaneous peripheral innervation and functional neural interactions with target compartments.

The research of Dr. Albrecht has highlighted specific pathologies from painful skin related to:

  • small caliber sensory innervation to the epidermis and interactions with epidermal keratinocyte chemistry and Langerhans cell function.
  • morphologic and molecular aberrations of small caliber sensory and sympathetic innervation to dermal vasculature, hair follicles, and sweat glands.
  • sensory stimulus transduction and integration among epidermal keratinocytes, vascular adventitia, muscle, and endothelium, sweat glands, and hair follicle compartments.

 

Dr. Albrecht holds a BS in psychology (1991) and a PhD in neuroscience (2001), both from the Pennsylvania State University.